Evidence desk · Issue 01 · 2026-08-17
The dose in the study is rarely the dose in the bottle.
An independent evidence desk for supplement formulas. We score what is on the label against the milligrams used in human studies. We do not rank “best fat burners”. We publish coverage bars: milligrams on the facts panel versus milligrams in the trial the ad is borrowing.
Formula files
All files| Formula | Transparency | Dose-fit | What we actually found |
|---|---|---|---|
| Matcha Extreme Matcha powder blend | A | C | A disclosed 2.25 g matcha serving with spirulina, cactus fruit, and acerola. A cup of tea with extras — not a high-dose EGCG trial. |
| EnduNAD NAD / longevity blend | A | C | A NAD bottle without NR or NMN. The workhorse is 250 mg niacinamide. Several headline botanicals are milligram theatre. |
| Shilajit Extreme Shilajit / men’s vitality blend | A | C | 200 mg PrimaVie is a real, purified extract — at half the daily milligrams used in the infertility trial people quote. |
| Fat Burn Active Multi-stim thermogenic | F | F | Eleven named actives, including forskolin, EGCG, synephrine, and caffeine — with almost no milligrams on the public label. |
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Ingredient monographs
Each file opens with a one-sentence verdict, then the study-dose band, evidence grades by outcome, and what remains unknown.
- Caffeine
The most replicated stimulant in human trials. Alertness is real. Fat loss from caffeine alone is small.
Study dose · 40–300 mg, often 3 mg/kg for performance
- L-theanine
The reason matcha feels different from an espresso. Evidence is strongest when it is paired with caffeine, at 100–200 mg.
Study dose · 100–200 mg, usually with 40–150 mg caffeine
- EGCG
The headline catechin in green tea. Weight-loss trials used concentrated extracts, not a cup of matcha.
Study dose · 300–800 mg EGCG/day in extract trials
- Forskolin
A lab tool that raises cAMP. Human fat-loss evidence is thin, and most bottles never state milligrams.
Study dose · 250 mg of 10% forskolin, twice daily (500 mg extract/day)
- Glucomannan
One of the few weight-related fibres with an authorised EU health claim — at 3 grams a day, with meals, in a calorie deficit.
Study dose · ~3 g/day, divided, with plenty of water
- Shilajit
A standardised extract has a couple of human trials. Raw tar from the internet does not inherit those trials.
Study dose · Often 200–250 mg twice daily of purified extract
- Niacin
A real NAD precursor you can buy for coins. Longevity claims usually belong to NR and NMN, which are not the same salt.
Study dose · Deficiency: tens of mg. Pharmacologic niacin: 500–2,000 mg nicotinic acid. NAD-booster trials more often use 300–1,000 mg NR.
- Synephrine
A relative of ephedrine with milder data and a worse reputation when stacked with caffeine.
Study dose · 10–50 mg p-synephrine
A coverage bar, not a star rating
100% means the facts panel meets the human-trial milligrams we cite. Blank hatch means the milligrams were not published. Marketing adjectives do not fill the bar.
Guides
- Green tea extract is not a bowl of matcha
The RCT your sales page cites probably used hundreds of milligrams of isolated EGCG. Culinary matcha is a different exposure.
- Niacin, NR, and NMN are not interchangeable
All three can feed NAD biology. They do not share a clinical literature, a milligram chart, or a side-effect profile.
- Caffeine plus L-theanine, at the doses that were actually studied
The calm-focus stack is real. It is also a capsule protocol that tea only approximates.
Worked example
EnduNAD is B3 in a longevity costume
No NR. No NMN. 250 mg niacinamide is a real dose. ~1 mg resveratrol is not. The file is the point of this desk.